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CPEB1 Mediates Epithelial-to-Mesenchyme Transition and Breast Cancer Metastasis
In mouse mammary epithelial cells, CPEB1 mediates the apical localization of ZO-1 mRNA, which encodes a critical tight junction component. In mice lacking CPEB1 and in cultured cells from which CPEB has been depleted, randomly distributed ZO-1 mRNA leads to the loss of cell polarity. We have investi...
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| Publicado en: | Oncogene |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4809797/ https://ncbi.nlm.nih.gov/pubmed/26411364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.350 |
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