Aberrant Activation of TGF-β in Subchondral Bone at the Onset of Rheumatoid Arthritis Joint Destruction

Rheumatoid arthritis (RA) is an autoimmune disease that often leads to joint destruction. A myriad of drugs targeting the immune abnormalities and downstream inflammatory cascades have been developed, but the joint destruction is not effectively halted. Here we report that aberrant activation of TGF...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Xu, Xin, Zheng, Liwei, Bian, Qin, Xie, Liang, Liu, Wenlong, Zhen, Gehua, Crane, Janet L, Zhou, Xuedong, Cao, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809636/
https://ncbi.nlm.nih.gov/pubmed/25967237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2550
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