MiR-138 Acts as a Tumor Suppressor by Targeting EZH2 and Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells

Chemotherapeutic insensitivity remains a major obstacle to treating osteosarcoma effectively. Recently, increasing evidence has suggested that microRNAs (miRNAs) are involved in drug resistance. However, the effect of miR-138 on cisplatin chemoresistance in osteosarcoma has not been reported. We use...

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Bibliographic Details
Published in:PLoS One
Main Authors: Zhu, Ziqiang, Tang, Jinshan, Wang, Jianqiang, Duan, Gang, Zhou, Lei, Zhou, Xiaoqing
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809565/
https://ncbi.nlm.nih.gov/pubmed/27019355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150026
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