Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition

Beat-to-beat variability in repolarization (BVR) has been proposed as an arrhythmic risk marker for disease and pharmacological action. The mechanisms are unclear but BVR is thought to be a cell level manifestation of ion channel stochasticity, modulated by cell-to-cell differences in ionic conducta...

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Bibliographic Details
Published in:	PLoS One
Main Authors:	Pueyo, E., Dangerfield, C. E., Britton, O. J., Virág, L., Kistamás, K., Szentandrássy, N., Jost, N., Varró, A., Nánási, P. P., Burrage, K., Rodríguez, B.
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2016
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4809506/ https://ncbi.nlm.nih.gov/pubmed/27019293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151461
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Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition

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