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Antibody-catalyzed reversal of chemoselectivity.

A monoclonal antibody, 14D9, which has been elicited against a cationic hapten, N-alkyl-N-methyl-3-glutarylamidomethyl piperidinium, in which alkyl = [4-(2-hydroxyethylamido)carbonyl]phenylmethyl, is capable of inverting the intrinsic order of reactivity in a series of structurally related enol ethe...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Sinha, S C, Keinan, E, Reymond, J L
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265647/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11910
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