Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

Tuberculosis remains second only to HIV/AIDS as the leading cause of mortality worldwide due to a single infectious agent(1). Despite chemotherapy, the global tuberculosis epidemic has intensified because of HIV co-infection, the lack of an effective vaccine and the emergence of multi-drug-resistant...

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Publicado no:Nature
Main Authors: Mayer-Barber, Katrin D., Andrade, Bruno B., Oland, Sandra D., Amaral, Eduardo P., Barber, Daniel L., Gonzales, Jacqueline, Derrick, Steven C., Shi, Ruiru, Kumar, Nathella Pavan, Wei, Wang, Yuan, Xing, Zhang, Guolong, Cai, Ying, Babu, Subash, Catalfamo, Marta, Salazar, Andres M., Via, Laura E., Barry, Clifton E., Sher, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809146/
https://ncbi.nlm.nih.gov/pubmed/24990750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13489
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