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Synergistic Transcription Activation by Maf and Sox and Their Subnuclear Localization Are Disrupted by a Mutation in Maf That Causes Cataract

Crystallin genes are selectively expressed during lens development. Maf and Sox family proteins synergistically enhanced γF-crystallin promoter activity in a lens cell line. Mutational analysis of the γF-crystallin promoter identified a composite regulatory element containing nonconsensus Maf and So...

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Autores principales: Rajaram, Nirmala, Kerppola, Tom K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC480896/
https://ncbi.nlm.nih.gov/pubmed/15199128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.5694-5709.2004
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