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Inscribing Optical Excitability to Non-Excitable Cardiac Cells: Viral Delivery of Optogenetic Tools in Primary Cardiac Fibroblasts

We describe in detail a method to introduce optogenetic actuation tools, a mutant version of channelrhodopsin- 2, ChR2(H134R), and archaerhodopsin (ArchT), into primary cardiac fibroblasts (cFB) in vitro by adenoviral infection to yield quick, robust, and consistent expression. Instructions on adjus...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Yu, Jinzhu, Entcheva, Emilia
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808651/
https://ncbi.nlm.nih.gov/pubmed/26965132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3512-3_21
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