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Gene delivery using calcium phosphate nanoparticles: Optimization of the transfection process and the effects of citrate and poly(l-lysine) as additives

Despite the long history of nanoparticulate calcium phosphate (CaP) as a non-viral transfection agent, there has been limited success in attempts to optimize its properties for transfection comparable in efficiency to that of viral vectors. Here we focus on the optimization of: (a) CaP nanoparticle...

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Detalhes bibliográficos
Publicado no:J Colloid Interface Sci
Main Authors: Khan, Mohammed A., Wu, Victoria M., Ghosh, Shreya, Uskoković, Vuk
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808621/
https://ncbi.nlm.nih.gov/pubmed/26971068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcis.2016.03.007
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