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Aminoacyl tRNA Synthetase Deficiency Promotes Angiogenesis via the Unfolded Protein Response Pathway
OBJECTIVE: Understanding the mechanisms regulating normal and pathologic angiogenesis is of great scientific and clinical interest. In this report, we show that mutations in two different aminoacyl tRNA synthetases, threonyl tRNA synthetase (tars(y58)) or isoleucyl tRNA synthetase (iars(y68)), lead...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4808418/ https://ncbi.nlm.nih.gov/pubmed/26821951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307087 |
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