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The link between abnormal calcium handling and electrical instability in acquired long QT syndrome – does calcium precipitate arrhythmic storms?

Release of Ca(2+) ions from sarcoplasmic reticulum (SR) into myocyte cytoplasm and their binding to troponin C is the final signal form myocardial contraction. Synchronous contraction of ventricular myocytes is necessary for efficient cardiac pumping function. This requires both shuttling of Ca(2+)...

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Detalhes bibliográficos
Publicado no:Prog Biophys Mol Biol
Main Authors: Němec, Jan, Kim, Jong J., Salama, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808372/
https://ncbi.nlm.nih.gov/pubmed/26631594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2015.11.003
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