Impact of Surotomycin on the Gut Microbiota of Healthy Volunteers in a Phase 1 Clinical Trial

Clostridium difficile-associated diarrhea has been associated with disruption of the normal intestinal microbiota, particularly the Bacteroides fragilis group and Prevotella species. Surotomycin is a bactericidal cyclic lipopeptide in development for treatment of Clostridium difficile-associated dia...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Citron, Diane M., Tyrrell, Kerin L., Dale, Suzanne E., Chesnel, Laurent, Goldstein, Ellie J. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808227/
https://ncbi.nlm.nih.gov/pubmed/26787687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02531-15
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