Association of Novel Nonsynonymous Single Nucleotide Polymorphisms in ampD with Cephalosporin Resistance and Phylogenetic Variations in ampC, ampR, ompF, and ompC in Enterobacter cloacae Isolates That Are Highly Resistant to Carbapenems

In Enterobacter cloacae, the genetic lesions associated with derepression of the AmpC β-lactamase include diverse single nucleotide polymorphisms (SNPs) and/or indels in the ampD and ampR genes and SNPs in ampC, while diverse SNPs in the promoter region or SNPs/indels within the coding sequence of o...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Babouee Flury, Baharak, Ellington, Matthew J., Hopkins, Katie L., Turton, Jane F., Doumith, Michel, Loy, Richard, Staves, Peter, Hinic, Vladimira, Frei, Reno, Woodford, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808197/
https://ncbi.nlm.nih.gov/pubmed/26856839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02835-15
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