Benznidazole Extended-Release Tablets for Improved Treatment of Chagas Disease: Preclinical Pharmacokinetic Study

Benznidazole (BNZ) is the first-line drug for the treatment of Chagas disease. The drug is available in the form of immediate-release tablets for 100-mg (adult) and 12.5-mg (pediatric) doses. The drug is administered two or three times daily for 60 days. The high frequency of daily administrations a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Davanço, Marcelo Gomes, Campos, Michel Leandro, Rosa, Talita Atanazio, Padilha, Elias Carvalho, Alzate, Alejandro Henao, Rolim, Larissa Araújo, Rolim-Neto, Pedro José, Peccinini, Rosângela Gonçalves
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808161/
https://ncbi.nlm.nih.gov/pubmed/26883698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02506-15
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