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Garcinol Inhibits GCN5-Mediated Lysine Acetyltransferase Activity and Prevents Replication of the Parasite Toxoplasma gondii

Lysine acetylation is a critical posttranslational modification that influences protein activity, stability, and binding properties. The acetylation of histone proteins in particular is a well-characterized feature of gene expression regulation. In the protozoan parasite Toxoplasma gondii, a number...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Jeffers, Victoria, Gao, Hongyu, Checkley, Lisa A., Liu, Yunlong, Ferdig, Michael T., Sullivan, William J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808158/
https://ncbi.nlm.nih.gov/pubmed/26810649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03059-15
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