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Hyperpolarization-independent maturation and refinement of GABA/glycinergic connections in the auditory brain stem

During development GABA and glycine synapses are initially excitatory before they gradually become inhibitory. This transition is due to a developmental increase in the activity of neuronal potassium-chloride cotransporter 2 (KCC2), which shifts the chloride equilibrium potential (E(Cl)) to values m...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Lee, Hanmi, Bach, Eva, Noh, Jihyun, Delpire, Eric, Kandler, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808136/
https://ncbi.nlm.nih.gov/pubmed/26655825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00926.2015
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