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Epigenetic therapy overcomes treatment resistance in T-cell prolymphocytic leukemia

T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell neoplasm with distinct features and an aggressive clinical course. Early relapse and short overall survival are commonplace. Use of the monoclonal anti-CD52 antibody alemtuzumab has improved the rate of complete remission and duration o...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Hasanali, Zainul S., Saroya, Bikramajit Singh, Stuart, August, Shimko, Sara, Evans, Juanita, Shah, Mithun Vinod, Sharma, Kamal, Leshchenko, Violetta V., Parekh, Samir, Loughran, Thomas, Epner, Elliot
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807901/
https://ncbi.nlm.nih.gov/pubmed/26109102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa5079
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