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Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer

BACKGROUND: Glycogen synthase kinase-3β (GSK-3β) is a multifunctional serine/threonine kinase that plays an important role in cancer tumorigenesis and progression. We investigated the role of the GSK-3β inhibitor AZD1080 in ovarian cancer cell lines. METHODS: A2780 and OVCAR3 ovarian cancer cell lin...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Chen, Shuo, Sun, Kai-Xuan, Feng, Miao-Xiao, Sang, Xiu-Bo, Liu, Bo-Liang, Zhao, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807899/
https://ncbi.nlm.nih.gov/pubmed/27051274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S102506
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