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A Unified Hypothesis of Early- and Late-Onset Alzheimer’s Disease Pathogenesis
Early-onset familial Alzheimer’s disease (EOFAD) and late-onset sporadic AD (LOSAD) both follow a similar pathological and biochemical course that includes: neuron and synapse loss and dysfunction, microvascular damage, microgliosis, extracellular amyloid-β deposition (Aβ), and the deposition of pho...
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| Publicado no: | J Alzheimers Dis |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807856/ https://ncbi.nlm.nih.gov/pubmed/26402752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-143210 |
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