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A Unified Hypothesis of Early- and Late-Onset Alzheimer’s Disease Pathogenesis

Early-onset familial Alzheimer’s disease (EOFAD) and late-onset sporadic AD (LOSAD) both follow a similar pathological and biochemical course that includes: neuron and synapse loss and dysfunction, microvascular damage, microgliosis, extracellular amyloid-β deposition (Aβ), and the deposition of pho...

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Bibliografski detalji
Izdano u:J Alzheimers Dis
Glavni autori: Atwood, Craig S., Bowen, Richard L.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807856/
https://ncbi.nlm.nih.gov/pubmed/26402752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-143210
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