Towards Rational Design of a Toxoid Vaccine against the Heat-Stable Toxin of Escherichia coli

Enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrheal disease and death in children <5 years old. ETEC strains that express the heat-stable toxin (ST), with or without the heat-labile toxin, are among the four most important diarrhea-causing pathogens. This makes ST an attrac...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Taxt, Arne M., Diaz, Yuleima, Aasland, Rein, Clements, John D., Nataro, James P., Sommerfelt, Halvor, Puntervoll, Pål
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807477/
https://ncbi.nlm.nih.gov/pubmed/26883587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01225-15
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