Mice with Genetic Deletion of Group VIA Phospholipase A(2)β Exhibit Impaired Macrophage Function and Increased Parasite Load in Trypanosoma cruzi-Induced Myocarditis

Trypanosoma cruzi infection, which is the etiological agent of Chagas disease, is associated with intense inflammation during the acute and chronic phases. The pathological progression of Chagas disease is influenced by the infiltration and transmigration of inflammatory cells across the endothelium...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Sharma, Janhavi, Blase, Jennifer R., Hoft, Daniel F., Marentette, John O., Turk, John, McHowat, Jane
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807476/
https://ncbi.nlm.nih.gov/pubmed/26857573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01564-15
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