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Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury

The low-density lipoprotein receptor (LDLR) pathway is a negative feedback system that plays important roles in the regulation of plasma and intracellular cholesterol homeostasis. To maintain a cholesterol homeostasis, LDLR expression is tightly regulated by sterol regulatory element-binding protein...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Zhang, Yang, Ma, Kun Ling, Ruan, Xiong Zhong, Liu, Bi Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807419/
https://ncbi.nlm.nih.gov/pubmed/27019638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.14027
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