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Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression

Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor regulating the expression of genes involved in xenobiotic response. Recent studies have suggested that AhR plays essential roles not only in xenobiotic detoxification but also energy metabolism. Thus, in this study, we studie...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wada, Taira, Sunaga, Hiroshi, Miyata, Kazuki, Shirasaki, Haruno, Uchiyama, Yuki, Shimba, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807284/
https://ncbi.nlm.nih.gov/pubmed/26865635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693655
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