Alternative Roles of STAT3 and MAPK Signaling Pathways in the MMPs Activation and Progression of Lung Injury Induced by Cigarette Smoke Exposure in ACE2 Knockout Mice

Inflammation-mediated abnormalities in the renin-angiotensin system (RAS) and expression of matrix metalloproteinases (MMPs) are implicated in the pathogenesis of lung injury. Angiotensin converting enzyme II (ACE2), an angiotensin converting enzyme (ACE) homologue that displays antagonist effects o...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Hung, Yi-Han, Hsieh, Wen-Yeh, Hsieh, Jih-Sheng, Liu, Fon-Chang, Tsai, Chin-Hung, Lu, Li-Che, Huang, Chen-Yi, Wu, Chien-Liang, Lin, Chih-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807164/
https://ncbi.nlm.nih.gov/pubmed/27019629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13379
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