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Microparticle-Induced Coagulation Relates to Coronary Artery Atherosclerosis in Severe Aortic Valve Stenosis

BACKGROUND: Circulating microparticles (MPs) derived from endothelial cells and blood cells bear procoagulant activity and promote thrombin generation. Thrombin exerts proinflammatory effects mediating the progression of atherosclerosis. Aortic valve stenosis may represent an atherosclerosis-like pr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Horn, Patrick, Erkilet, Gülsüm, Veulemans, Verena, Kröpil, Patric, Schurgers, Leon, Zeus, Tobias, Heiss, Christian, Kelm, Malte, Westenfeld, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807100/
https://ncbi.nlm.nih.gov/pubmed/27010400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151499
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