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High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Posaconazole and Vincristine in Rat Plasma

Purpose. Developing a validated HPLC-DAD method for simultaneous determination of posaconazole (PSZ) and vincristine (VCR) in rat plasma. Methods. PSZ, VCR, and itraconazole (ITZ) were extracted from 200 μL plasma using diethyl ether in the presence of 0.1 M sodium hydroxide solution. The organic la...

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Detalhes bibliográficos
Publicado no:Int J Anal Chem
Main Authors: Khalil, Hadeel A., El-Yazbi, Ahmed F., Belal, Tarek S., Hamdy, Dalia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807048/
https://ncbi.nlm.nih.gov/pubmed/27034675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/743915
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