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Successful Phenotype Improvement following Gene Therapy for Severe Hemophilia A in Privately Owned Dogs
Severe hemophilia A (HA) is an inherited bleeding disorder characterized by <1% of residual factor VIII (FVIII) clotting activity. The disease affects several mammals including dogs, and, like humans, is associated with high morbidity and mortality. In gene therapy using adeno-associated viral (A...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807047/ https://ncbi.nlm.nih.gov/pubmed/27011017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151800 |
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