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Metabolic modeling of dynamic brain (13)C NMR multiplet data: Concepts and simulations with a two-compartment neuronal-glial model

Metabolic modeling of dynamic (13)C labeling curves during infusion of (13)C-labeled substrates allows quantitative measurements of metabolic rates in vivo. However metabolic modeling studies performed in the brain to date have only modeled time courses of total isotopic enrichment at individual car...

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Detalhes bibliográficos
Publicado no:Neurochem Res
Main Authors: Shestov, Alexander A., Valette, Julien, Deelchand, Dinesh K., Uğurbil, Kâmil, Henry, Pierre-Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806787/
https://ncbi.nlm.nih.gov/pubmed/22528840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0782-5
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