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The Fur homologue BosR requires Arg39 to activate rpoS transcription in Borrelia burgdorferi and thereby direct spirochaete infection in mice
Borrelia burgdorferi is the causative agent of Lyme disease. In B. burgdorferi, RpoS controls the expression of virulence genes needed for mammalian infection. The Fur homologue BosR regulates the transcription of rpoS and therefore BosR determines, albeit indirectly, the infection status of the spi...
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| Udgivet i: | Microbiology (Reading) |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Microbiology Society
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806591/ https://ncbi.nlm.nih.gov/pubmed/26318670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.000166 |
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