Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction

BACKGROUND: Eliminating cancer stem cells (CSCs) has been suggested for prevention of tumor recurrence and metastasis. Honokiol, an active compound of Magnolia officinalis, had been proposed to be a potential candidate drug for cancer treatment. We explored its effects on the elimination of oral CSC...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Huang, Jhy-Shrian, Yao, Chih-Jung, Chuang, Shuang-En, Yeh, Chi-Tai, Lee, Liang-Ming, Chen, Ruei-Ming, Chao, Wan-Ju, Whang-Peng, Jacqueline, Lai, Gi-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806492/
https://ncbi.nlm.nih.gov/pubmed/27012679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2265-6
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