Single nucleotide polymorphisms in apoptosis pathway are associated with response to imatinib therapy in chronic myeloid leukemia

BACKGROUND: The mechanism of action of imatinib is known to involve the Fas-mediated apoptosis pathway. Consequently inter-individual variations in this apoptosis pathway might be associated with imatinib response or resistance. METHODS: This study attempted to focus on eight genotypes in the apopto...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Zheng, Qiaoli, Cao, Jiang, Hamad, Nada, Kim, Hyeoung-Joon, Moon, Joon Ho, Sohn, Sang Kyun, Jung, Chul Won, Lipton, Jeffrey H., Kim, Dennis Dong Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806489/
https://ncbi.nlm.nih.gov/pubmed/27009330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0837-5
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