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Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation

Hepatitis C virus (HCV) has long been observed to take advantage of the host mitochondria to support viral replication and assembly. The HCV core protein has been implicated to fragment host mitochondria. In this report, we have discovered that the non-structural protein 5A (NS5A) plays an instructi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Siu, Gavin Ka Yu, Zhou, Fan, Yu, Mei Kuen, Zhang, Leiliang, Wang, Tuanlao, Liang, Yongheng, Chen, Yangchao, Chan, Hsiao Chang, Yu, Sidney
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806301/
https://ncbi.nlm.nih.gov/pubmed/27010100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23464
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