RORγt(+) cells selectively express redundant cation channels linked to the Golgi apparatus

Retinoid-related orphan receptor gamma t (RORγt) is a master transcription factor central to type 17 immunity involving cells such as T helper 17, group 3 innate lymphoid cells or IL-17-producing γδ T cells. Here we show that the intracellular ion channel TMEM176B and its homologue TMEM176A are stro...

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Pubblicato in:Sci Rep
Autori principali: Drujont, Lucile, Lemoine, Aurélie, Moreau, Aurélie, Bienvenu, Géraldine, Lancien, Mélanie, Cens, Thierry, Guillot, Flora, Bériou, Gaëlle, Bouchet-Delbos, Laurence, Fehling, Hans Jörg, Chiffoleau, Elise, Nicot, Arnaud B., Charnet, Pierre, Martin, Jérôme C., Josien, Régis, Cuturi, Maria Cristina, Louvet, Cédric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806298/
https://ncbi.nlm.nih.gov/pubmed/27009467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23682
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