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The Dual Function of Reactive Oxygen/Nitrogen Species in Bioenergetics and Cell Death: The Role of ATP Synthase

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) targeting mitochondria are major causative factors in disease pathogenesis. The mitochondrial permeability transition pore (PTP) is a mega-channel modulated by calcium and ROS/RNS modifications and it has been described to play a cruc...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Kaludercic, Nina, Giorgio, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806282/
https://ncbi.nlm.nih.gov/pubmed/27034734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3869610
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