Cholesterol-Enriched Domain Formation Induced by Viral-Encoded, Membrane-Active Amphipathic Peptide

The α-helical (AH) domain of the hepatitis C virus nonstructural protein NS5A, anchored at the cytoplasmic leaflet of the endoplasmic reticulum, plays a role in viral replication. However, the peptides derived from this domain also exhibit remarkably broad-spectrum virocidal activity, raising questi...

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書目詳細資料
發表在:Biophys J
Main Authors: Hanson, Joshua M., Gettel, Douglas L., Tabaei, Seyed R., Jackman, Joshua, Kim, Min Chul, Sasaki, Darryl Y., Groves, Jay T., Liedberg, Bo, Cho, Nam-Joon, Parikh, Atul N.
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2016
主題:
Membranes
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806215/
https://ncbi.nlm.nih.gov/pubmed/26745420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.11.032
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