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Determinants of Cx43 Channel Gating and Permeation: The Amino Terminus

Separate connexin domains partake in proposed gating mechanisms of gap junction channels. The amino-terminus (NT) domains, which contribute to voltage sensing, may line the channel’s cytoplasmic-facing funnel surface, stabilize the channel’s overall structure through interactions with the transmembr...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Ek Vitorín, José F., Pontifex, Tasha K., Burt, Janis M.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805864/
https://ncbi.nlm.nih.gov/pubmed/26745416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.054
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