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A phase I dose escalation study of S-1 with concurrent radiotherapy in elderly patients with esophageal cancer

BACKGROUND: Concurrent chemoradiotherapy (CRT) with 5-fluorouracil (5-FU) and cisplatin (CDDP) are often associated with significant incidence of toxic effects in elderly patients with esophageal cancer. This phase I trial was designed to determine the maximum tolerated dose (MTD) and dose-limiting...

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Detalhes bibliográficos
Publicado no:J Thorac Dis
Main Authors: Ji, Yongling, Qiu, Guoqing, Sheng, Liming, Sun, Xiaojiang, Zheng, Yuanda, Chen, Ming, Du, Xianghui
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805812/
https://ncbi.nlm.nih.gov/pubmed/27076940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2016.02.70
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