Ionomycin Treatment Renders NK Cells Hyporesponsive

Natural killer cells are cytotoxic lymphocytes important in immune responses to cancer and multiple pathogens. However, chronic activation of NK cells can induce a hyporesponsive state. The molecular basis of the mechanisms underlying the generation and maintenance of this hyporesponsive condition a...

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Bibliographic Details
Published in:PLoS One
Main Authors: Romera-Cárdenas, Gema, Thomas, L. Michael, Lopez-Cobo, Sheila, García-Cuesta, Eva M., Long, Eric O., Reyburn, Hugh T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805247/
https://ncbi.nlm.nih.gov/pubmed/27007115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150998
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