Earth Mover’s Distance (EMD): A True Metric for Comparing Biomarker Expression Levels in Cell Populations

Changes in the frequencies of cell subsets that (co)express characteristic biomarkers, or levels of the biomarkers on the subsets, are widely used as indices of drug response, disease prognosis, stem cell reconstitution, etc. However, although the currently available computational “gating” tools acc...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Orlova, Darya Y., Zimmerman, Noah, Meehan, Stephen, Meehan, Connor, Waters, Jeffrey, Ghosn, Eliver E. B., Filatenkov, Alexander, Kolyagin, Gleb A., Gernez, Yael, Tsuda, Shanel, Moore, Wayne, Moss, Richard B., Herzenberg, Leonore A., Walther, Guenther
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805242/
https://ncbi.nlm.nih.gov/pubmed/27008164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151859
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