Earth Mover’s Distance (EMD): A True Metric for Comparing Biomarker Expression Levels in Cell Populations

Changes in the frequencies of cell subsets that (co)express characteristic biomarkers, or levels of the biomarkers on the subsets, are widely used as indices of drug response, disease prognosis, stem cell reconstitution, etc. However, although the currently available computational “gating” tools acc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Orlova, Darya Y., Zimmerman, Noah, Meehan, Stephen, Meehan, Connor, Waters, Jeffrey, Ghosn, Eliver E. B., Filatenkov, Alexander, Kolyagin, Gleb A., Gernez, Yael, Tsuda, Shanel, Moore, Wayne, Moss, Richard B., Herzenberg, Leonore A., Walther, Guenther
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805242/
https://ncbi.nlm.nih.gov/pubmed/27008164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151859
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