Inducing Acute Traumatic Coagulopathy In Vitro: The Effects of Activated Protein C on Healthy Human Whole Blood

INTRODUCTION: Acute traumatic coagulopathy has been associated with shock and tissue injury, and may be mediated via activation of the protein C pathway. Patients with acute traumatic coagulopathy have prolonged PT and PTT, and decreased activity of factors V and VIII; they are also hypocoagulable b...

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Udgivet i:PLoS One
Main Authors: Howard, Benjamin M., Kornblith, Lucy Z., Cheung, Christopher K., Kutcher, Matthew E., Miyazawa, Byron Y., Vilardi, Ryan F., Cohen, Mitchell J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805205/
https://ncbi.nlm.nih.gov/pubmed/27008408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150930
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