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The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction

Sonic hedgehog (SHH) and its signaling have been identified in several human cancers, and increased levels of its expression appear to correlate with disease progression and metastasis. However, the role of SHH in bone destruction associated with oral squamous cell carcinomas is still unclear. In th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shimo, Tsuyoshi, Matsumoto, Kenichi, Takabatake, Kiyofumi, Aoyama, Eriko, Takebe, Yuichiro, Ibaragi, Soichiro, Okui, Tatsuo, Kurio, Naito, Takada, Hiroyuki, Obata, Kyoichi, Pang, Pai, Iwamoto, Masahiro, Nagatsuka, Hitoshi, Sasaki, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805186/
https://ncbi.nlm.nih.gov/pubmed/27007126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151731
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