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Folding cooperativity in a 3-stranded β-sheet model

The thermodynamic behavior of a previously designed three-stranded β-sheet was studied via several µs of standard and replica exchange molecular dynamics simulations. The system is shown to populate at least four thermodynamic minima, including 2 partially folded states in which only a single hairpi...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Roe, Daniel R., Hornak, Viktor, Simmerling, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805115/
https://ncbi.nlm.nih.gov/pubmed/16095612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2005.07.036
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