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Tissue-aware data integration approach for the inference of pathway interactions in metazoan organisms

Motivation: Leveraging the large compendium of genomic data to predict biomedical pathways and specific mechanisms of protein interactions genome-wide in metazoan organisms has been challenging. In contrast to unicellular organisms, biological and technical variation originating from diverse tissues...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Park, Christopher Y., Krishnan, Arjun, Zhu, Qian, Wong, Aaron K., Lee, Young-Suk, Troyanskaya, Olga G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804827/
https://ncbi.nlm.nih.gov/pubmed/25431329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu786
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