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Preservation of methylated CpG dinucleotides in human CpG islands
BACKGROUND: CpG dinucleotides are extensively underrepresented in mammalian genomes. It is widely accepted that genome-wide CpG depletion is predominantly caused by an elevated CpG > TpG mutation rate due to frequent cytosine methylation in the CpG context. Meanwhile the CpG content in genomic re...
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| Опубликовано в: : | Biol Direct |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4804638/ https://ncbi.nlm.nih.gov/pubmed/27005429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-016-0113-x |
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