Direct Hydrogel Encapsulation of Pluripotent Stem Cells Enables Ontomimetic Differentiation and Growth of Engineered Human Heart Tissues

Human engineered heart tissues have potential to revolutionize cardiac development research, drug-testing, and treatment of heart disease; however, implementation is limited by the need to use pre-differentiated cardiomyocytes (CMs). Here we show that by providing a 3D poly(ethylene glycol)-fibrinog...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Kerscher, Petra, Turnbull, Irene C, Hodge, Alexander J, Kim, Joonyul, Seliktar, Dror, Easley, Christopher J, Costa, Kevin D, Lipke, Elizabeth A
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804626/
https://ncbi.nlm.nih.gov/pubmed/26826618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.12.011
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