The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study

BACKGROUND: The durability of isoniazid preventive therapy (IPT) in preventing tuberculosis (TB) is limited in high-prevalence settings. The underlying mechanism (reactivation of persistent latent TB or reinfection) is not known. We aimed to investigate the timing of TB incidence during and after IP...

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Pubblicato in:BMC Med
Autori principali: Hermans, Sabine M., Grant, Alison D., Chihota, Violet, Lewis, James J., Vynnycky, Emilia, Churchyard, Gavin J., Fielding, Katherine L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804575/
https://ncbi.nlm.nih.gov/pubmed/27004413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-016-0589-3
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