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Comparative effects of immediate‐release and extended‐release aspirin on basal and bradykinin‐stimulated excretion of thromboxane and prostacyclin metabolites

A goal of aspirin therapy is to inhibit thromboxane production and platelet aggregation without inhibiting endothelial production of the vasodilator and anti‐thrombotic prostacyclin. This study tested the hypothesis that extended‐release aspirin (NHP‐554C) would have increased selectivity for inhibi...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Gamboa, Jorge L., Devin, Jessica K., Ramirez, Claudia E., Yu, Chang, Nian, Hui, Lee, Rhonda H., Brown, Nancy J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804312/
https://ncbi.nlm.nih.gov/pubmed/27069632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.221
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