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Comparative effects of immediate‐release and extended‐release aspirin on basal and bradykinin‐stimulated excretion of thromboxane and prostacyclin metabolites

A goal of aspirin therapy is to inhibit thromboxane production and platelet aggregation without inhibiting endothelial production of the vasodilator and anti‐thrombotic prostacyclin. This study tested the hypothesis that extended‐release aspirin (NHP‐554C) would have increased selectivity for inhibi...

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Bibliografische gegevens
Gepubliceerd in:Pharmacol Res Perspect
Hoofdauteurs: Gamboa, Jorge L., Devin, Jessica K., Ramirez, Claudia E., Yu, Chang, Nian, Hui, Lee, Rhonda H., Brown, Nancy J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804312/
https://ncbi.nlm.nih.gov/pubmed/27069632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.221
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