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Effect of GLP-1 Receptor Activation on Offspring Kidney Health in a Rat Model of Maternal Obesity

Maternal obesity is associated with an increased risk of chronic disease in offspring, including type 2 diabetes (T2D). Exendin-4 (Exd-4) activates the glucagon like peptide-1 (GLP-1) receptor thereby decreasing serum glucose levels and body weight. In addition, Exd-4 has been shown to reduce renal...

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Publicat a:Sci Rep
Autors principals: Glastras, Sarah J., Chen, Hui, McGrath, Rachel T., Zaky, Amgad A., Gill, Anthony J., Pollock, Carol A., Saad, Sonia
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804207/
https://ncbi.nlm.nih.gov/pubmed/27004609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23525
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