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Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism

We have recently shown that increased hydrogen peroxide (H(2)O(2)) generation is involved in hypoxia–ischemia (HI)-mediated neonatal brain injury. H(2)O(2) can react with free iron to form the hydroxyl radical, through Fenton Chemistry. Thus, the objective of this study was to determine if there was...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lu, Qing, Harris, Valerie A., Rafikov, Ruslan, Sun, Xutong, Kumar, Sanjiv, Black, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804102/
https://ncbi.nlm.nih.gov/pubmed/26209813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.06.007
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