Val-->Ala mutations selectively alter helix-helix packing in the transmembrane segment of phage M13 coat protein.
Val-->Ala mutations within the effective transmembrane segment of a model single-spanning membrane protein, the 50-residue major coat (gene VIII) protein of bacteriophage M13, are shown to have sequence-dependent impacts on stabilization of membrane-embedded helical dimeric structures. Randomized mu...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11648 |
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